A SYNERGISTIC TRIAD OF CHEMOTHERAPY, IMMUNE CHECKPOINT INHIBITORS, AND CALORIC RESTRICTION MIMETICS ERADICATES TUMORS IN MICE

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

We have recently shown that chemotherapy with immunogenic cell death (ICD)-inducing agents can be advantageously combined with fasting regimens or caloric restriction mimetics (CRMs) to achieve superior tumor growth control via a T cell-dependent Dough Equipment:Commercial Dough Rollers mechanism.Here, we show that the blockade of the CD11b-depende

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Evaluation of the Impact of Stress Distribution on Polyurethane Trileaflet Heart Valve Leaflets in the Open Configuration by Employing Numerical Simulation

It is costly and time-consuming to design and manufacture functional polyurethane heart valve prototypes, to evaluate and comprehend their hemodynamic behaviour.To enhance Dough Equipment:Commercial Dough Rollers the rapid and effective design of replacement heart valves, to meet the minimum criteria of FDA and ISO regulations and specifications, a

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Prolonged rote learning produces delayed memory facilitation and metabolic changes in the hippocampus of the ageing human brain

Abstract Background Repeated rehearsal is one method by which verbal material may be transferred from short- to long-term memory.We hypothesised that extended engagement of memory structures through prolonged rehearsal would result nasal aspirator in enhanced efficacy of recall and also of brain structures implicated in new learning.Twenty-four nor

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